Publications From The Santos Lab

Posts tagged Chd1

The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output.

The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output.

Authors: Bulut-Karslioglu A, Macrae TA, Oses-Prieto JA, Covarrubias S, Percharde M, Ku G, Diaz A, McManus MT, Burlingame AL, Ramalho-Santos M.
Reference: Cell Stem Cell. 2018 Mar 1;22(3):369-383.e8. doi: 10.1016/j.stem.2018.02.004.
PMID: 29499153

Santos LabMarch 1, 2018Chd1, blastocyst, embryonic stem cells, euchromatin, hypertranscription, mTOR, permissive chromatin, ribosome, translation, 2018

Hypertranscription in Development, Stem Cells, and Regeneration.

Authors: Percharde M, Bulut-Karslioglu A, Ramalho-Santos M.
Reference: Dev Cell. 2017 Jan 9;40(1):9-21. doi: 10.1016/j.devcel.2016.11.010. Epub 2016 Dec 15. Review.
PMID: 27989554

Santos LabJanuary 9, 2017Chd1, Myc, cell competition, cell number normalization, development, hypertranscription, open chromatin, proliferation, regeneration, self-renewal, stem cells, 2017

Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription.

Authors: Koh FM, Lizama CO, Wong P, Hawkins JS, Zovein AC, Ramalho-Santos M.
Reference: Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1734-43. doi: 10.1073/pnas.1424850112. Epub 2015 Mar 23.
PMID: 25831528

Santos LabApril 7, 2015Chd1, definitive hematopoiesis, endothelial-to-hematopoietic transition, hemogenic endothelium, transcription, 2015