Unwind and transcribe: chromatin reprogramming in the early mammalian embryo. Authors: Biechele S, Lin CJ, Rinaudo PF, Ramalho-Santos M.Reference: Curr Opin Genet Dev. 2015 Oct;34:17-23. doi: 10.1016/j.gde.2015.06.003. Epub 2015 Jul 13. Review.PMID: 26183187 Read More Santos LabOctober 1, 20152015
Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Authors: Koh FM, Lizama CO, Wong P, Hawkins JS, Zovein AC, Ramalho-Santos M.Reference: Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1734-43. doi: 10.1073/pnas.1424850112. Epub 2015 Mar 23.PMID: 25831528 Read More Santos LabApril 7, 2015Chd1, definitive hematopoiesis, endothelial-to-hematopoietic transition, hemogenic endothelium, transcription, 2015
HiTSelect: a comprehensive tool for high-complexity-pooled screen analysis. Authors: Diaz AA, Qin H, Ramalho-Santos M, Song JS.Reference: Nucleic Acids Res. 2015 Feb 18;43(3):e16. doi: 10.1093/nar/gku1197. Epub 2014 Nov 26.PMID: 25428347 Read More Santos LabFebruary 18, 20152015
Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. Authors: Guzman-Ayala M, Sachs M, Koh FM, Onodera C, Bulut-Karslioglu A, Lin CJ, Wong P, Nitta R, Song JS, Ramalho-Santos M.Reference: Development. 2015 Jan 1;142(1):118-27. doi: 10.1242/dev.114843. Epub 2014 Dec 5.PMID: 25480920 Read More Santos LabJanuary 1, 2015Chromatin, Epiblast proliferation, Epigenetics, Pluripotency, Transcription, 2015