iPS cells: insights into basic biology.

Authors: Ramalho-Santos M.

Reference: Cell. 2009 Aug 21;138(4):616-8. doi: 10.1016/j.cell.2009.08.012.

PMID: 19703387

Abstract: The discovery that adult somatic cells can be induced to become pluripotent by overexpression of a few key transcription factors provides an exciting new window into the basic biology of pluripotency and differentiation.

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Parallel gateways to pluripotency: open chromatin in stem cells and development.

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Chd1 regulates open chromatin and pluripotency of embryonic stem cells.